Inadequate brain glycogen or sleep increases spreading depression susceptibility
نویسندگان
چکیده
منابع مشابه
P85: Spreading Depression in the Brain Cortex and Spinal Cord
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متن کاملBlood-brain glucose transfer in spreading depression.
Spreading depression in rat brain cortex is associated with a twofold increase of cerebral blood flow. It is not known whether this increase is coupled to increases of cerebral metabolic rate and glucose transport from blood to brain. During the passage of a single spreading depression, we measured blood-brain glucose transport and glucose metabolism in rat cerebral cortex by single intravenous...
متن کاملSpreading depression increases immunohistochemical staining of glial fibrillary acidic protein.
Reactive astrocytosis is a process by which astrocytes respond to brain injury by showing an increase in glial fibrillary acidic protein (GFAP) staining that is associated with hypertrophy and/or hyperplasia of these cells. Because spreading depression (SD) is a perturbation uncomplicated by neuronal necrosis and is seen in both in vivo and in vitro neural structures, we sought to determine whe...
متن کاملp85: spreading depression in the brain cortex and spinal cord
cortical spreading depression (csd) has been suggested to underlie some neurological disorders such as migraine. despite the intensity with which many investigators have studied sd in the brain, only a few studies have aimed to identify sd in the spinal cord. here we described the main characteristic features of sd in the spinal cord induced by different methods including various spinal cord in...
متن کاملElectrophysiological characteristics of hippocampal CA1 neurons after spreading depression-triggered epileptic activity in brain slices
Introduction: A close link between spreading depression (SD) and several neurological diseases such as epilepsy could be demonstrated in many experimental studies. Epilepsy is among the most common brain disorders. Despite a large number of investigations, its mechanisms have not been yet well elucidated. Hippocampus is one of the important structures involved in seizures. The aim of this st...
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ژورنال
عنوان ژورنال: Annals of Neurology
سال: 2018
ISSN: 0364-5134
DOI: 10.1002/ana.25122